AMD Ryzen Threadripper PRO 3995WX vs AMD EPYC 7543P

Updated Aug 2026 · Scored by the Let’s Compare Data Engine · How we score

For most buyers the AMD Ryzen Threadripper PRO 3995WX is the better pick — it scores 86/100 to the AMD EPYC 7543P's 67, leading on Core Specifications and Benchmark. Choose the AMD EPYC 7543P instead if you want to spend less.

Verdict

Our overall take, at a glance

AMD Ryzen Threadripper PRO 3995WX leads overall

AMD Ryzen Threadripper PRO 3995WX

AMD EPYC 7543P

Why it stands out

Core Specifications Cores: 64
Core Specifications Threads: 128
Core Specifications Base Power Consumption: 280 W (24% more)

Winner by category for AMD Ryzen Threadripper PRO 3995WX vs AMD EPYC 7543P
Category	AMD Ryzen Threadripper PRO 3995WX	AMD EPYC 7543P	Winner
Core Specifications	67	52	AMD Ryzen Threadripper PRO 3995WX
Integrated Graphics	0	0	Tie
Benchmark	96	74	AMD Ryzen Threadripper PRO 3995WX

In-depth analysisAI

AI-generated from the cited sources — may be incomplete or inaccurate; verify important details before deciding · generated Aug 2026.

AMD Ryzen Threadripper PRO 3995WX

AMD Ryzen microprocessors are x86-64 CPUs based on the Zen microarchitecture. The Ryzen family includes various processor lines such as Ryzen 3, Ryzen 5, and Ryzen Threadripper, which can feature up to 96 cores. Desktop processors include different generations like the Ryzen 1000, 2000, 3000, 4000, etc., series.

Best for N/A

Pros

Cons

AMD EPYC 7543P

The AMD EPYC 7543P is a 32-core server processor built on the Zen 3-based 'Milan' architecture. It is designed specifically for single-socket (1P) configurations, aiming to deliver high-density computing performance and efficiency for data centers without the added complexity of multi-socket setups.

Best for Single-socket enterprise servers aiming to maximize compute density while…Best for Virtualization environments looking to optimize costs associated with…

Pros

High-density performance featuring 32 cores optimized for single-processor configurations
Strong power efficiency and architectural advantages of the EPYC Milan generation
Helps lower software licensing costs that are charged on a per-socket basis

Cons

Limited strictly to single-socket systems, offering no pathway for dual-socket scale-up
Faces strong price and performance competition from alternative architectures like Intel's Ice Lake

Value for Money

Which is the better deal for the price

Pre-filled with launch prices where known — enter today's price for an up-to-date check. Use the same currency for both.

AMD Ryzen Threadripper PRO 3995WX

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AMD EPYC 7543P

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Performance

Higher benchmark score = faster

AMD Ryzen Threadripper PRO 3995WX82,018

AMD EPYC 7543P66,590

See the raw benchmark values →

Benchmark score — a measured indicator of raw performance, not a guarantee of real-world speed.

Review Videos

Hand-picked expert reviews for each product

Detailed Specifications

The full spec sheet, side by side

Core Specifications

Feature	AMD Ryzen Threadripper PRO 3995WX	AMD EPYC 7543P
Cores	64	32
Threads	128	64
Base Frequency	2.7 GHz	2.8 GHz4% more
Base Power Consumption	280 W24% more	225 W
Maximum Frequency	4.2 GHz14% more	3.7 GHz
Maximum Power Consumption	N/A	240 W
L1 Cache	4,096 KB100% more	2,048 KB
L2 Cache	32 MB100% more	16 MB
L3 Cache	256 MB	256 MB
Lithography Process	7 nm	N/A
Is unlocked	No	N/A

Integrated Graphics

Feature	AMD Ryzen Threadripper PRO 3995WX	AMD EPYC 7543P
Model	N/A	N/A

Benchmark

Feature	AMD Ryzen Threadripper PRO 3995WX	AMD EPYC 7543P
PassMark CPU Mark	82,01823% more	66,590

Specification Note

Specifications are compiled from official manufacturer data and other reliable internet sources. Some features may vary by region or model configuration.

Frequently Asked Questions

Common questions about AMD Ryzen Threadripper PRO 3995WX vs AMD EPYC 7543P comparison

Based on our overall comparison score, AMD Ryzen Threadripper PRO 3995WX rates higher at 89/100 versus 86/100 for AMD EPYC 7543P — a 3-point lead. AMD Ryzen Threadripper PRO 3995WX is the stronger overall pick, though the right choice still depends on which specs matter most to you; the full spec table above breaks down every difference.

AMD Ryzen Threadripper PRO 3995WX and AMD EPYC 7543P are compared side by side above across every spec in the cpus category — including performance, features and design — each scored 0–100 so you can see exactly where one leads the other. Our overall scores are 89/100 for AMD Ryzen Threadripper PRO 3995WX and 86/100 for AMD EPYC 7543P.

If you want the higher-rated cpus option overall, AMD Ryzen Threadripper PRO 3995WX (89/100) edges out AMD EPYC 7543P (86/100). But if AMD EPYC 7543P is cheaper or stronger on the specific specs you care about, it can still be the better buy — use the spec table and strengths profile above to decide.