AMD EPYC 7543P vs Intel Xeon Platinum 8380

Updated Aug 2026 · Scored by the Let’s Compare Data Engine · How we score

For most buyers the AMD EPYC 7543P is the better pick — it scores 85/100 to the Intel Xeon Platinum 8380's 67, leading on Core Specifications and Benchmark. Choose the Intel Xeon Platinum 8380 instead if you want to spend less.

Verdict

Our overall take, at a glance

AMD EPYC 7543P leads overall

AMD EPYC 7543P

Intel Xeon Platinum 8380

Why it stands out

Core Specifications Base Frequency: 2.8 GHz (22% more)
Core Specifications Maximum Frequency: 3.7 GHz (9% more)
Core Specifications L3 Cache: 256 MB (327% more)

Winner by category for AMD EPYC 7543P vs Intel Xeon Platinum 8380
Category	AMD EPYC 7543P	Intel Xeon Platinum 8380	Winner
Core Specifications	64	55	AMD EPYC 7543P
Integrated Graphics	0	0	Tie
Benchmark	96	73	AMD EPYC 7543P

In-depth analysisAI

AI-generated from the cited sources — may be incomplete or inaccurate; verify important details before deciding · generated Aug 2026.

AMD EPYC 7543P

The AMD EPYC 7543P is a 32-core server processor built on the Zen 3-based 'Milan' architecture. It is designed specifically for single-socket (1P) configurations, aiming to deliver high-density computing performance and efficiency for data centers without the added complexity of multi-socket setups.

Best for Single-socket enterprise servers aiming to maximize compute density while…Best for Virtualization environments looking to optimize costs associated with…

Pros

High-density performance featuring 32 cores optimized for single-processor configurations
Strong power efficiency and architectural advantages of the EPYC Milan generation
Helps lower software licensing costs that are charged on a per-socket basis

Cons

Limited strictly to single-socket systems, offering no pathway for dual-socket scale-up
Faces strong price and performance competition from alternative architectures like Intel's Ice Lake

Intel Xeon Platinum 8380

The Intel Xeon Platinum 8380 is a high-performance CPU designed for data center and enterprise computing environments. With its designation as a flagship model within the Xeon line, it provides advanced processing capabilities for demanding workloads. It is intended for organizations requiring maximum computational power in server infrastructure.

Best for Cloud ComputingBest for Database ServersBest for High-Performance Computing

Pros

Designed for critical enterprise and large-scale cloud deployments (index: 2)
Represents an advanced offering within the history of Intel Xeon processors (index: 2)
The 'Platinum' designation signifies a high tier of performance within its product family (index: 2)

Cons

It is highly specialized hardware, unsuitable for general desktop or consumer computing use cases (general knowledge)
Like many enterprise CPUs, performance heavily depends on the specific server architecture it operates within (general knowledge)

Value for Money

Which is the better deal for the price

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AMD EPYC 7543P

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Intel Xeon Platinum 8380

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Performance

Higher benchmark score = faster

AMD EPYC 7543P66,590

Intel Xeon Platinum 838062,318

See the raw benchmark values →

Benchmark score — a measured indicator of raw performance, not a guarantee of real-world speed.

Review Videos

Hand-picked expert reviews for each product

Detailed Specifications

The full spec sheet, side by side

Core Specifications

Feature	AMD EPYC 7543P	Intel Xeon Platinum 8380
Cores	32	40
Threads	64	80
Base Frequency	2.8 GHz22% more	2.3 GHz
Base Power Consumption	225 W	270 W20% more
Maximum Frequency	3.7 GHz9% more	3.4 GHz
Maximum Power Consumption	240 W	N/A
L1 Cache	2,048 KB	2,560 KB25% more
L2 Cache	16 MB	50 MB213% more
L3 Cache	256 MB327% more	60 MB
Lithography Process	N/A	10 nm
Is unlocked	N/A	No

Integrated Graphics

Feature	AMD EPYC 7543P	Intel Xeon Platinum 8380
Model	N/A	N/A

Benchmark

Feature	AMD EPYC 7543P	Intel Xeon Platinum 8380
PassMark CPU Mark	66,5907% more	62,318

Specification Note

Specifications are compiled from official manufacturer data and other reliable internet sources. Some features may vary by region or model configuration.

Frequently Asked Questions

Common questions about AMD EPYC 7543P vs Intel Xeon Platinum 8380 comparison

They are closely matched: AMD EPYC 7543P scores 86/100 and Intel Xeon Platinum 8380 scores 85/100 in our overall comparison — within 1 point. Neither is a clear winner overall, so the decision comes down to the specific features and price that matter most to you.

AMD EPYC 7543P and Intel Xeon Platinum 8380 are compared side by side above across every spec in the cpus category — including performance, features and design — each scored 0–100 so you can see exactly where one leads the other. Our overall scores are 86/100 for AMD EPYC 7543P and 85/100 for Intel Xeon Platinum 8380.

It's close — AMD EPYC 7543P (86/100) and Intel Xeon Platinum 8380 (85/100) score almost the same. Pick based on price and the individual specs that matter most to you; the comparison above shows where each one pulls ahead.